Persistent pulmonary hypertension of the newborn

Persistent Pulmonary Hypertension of the Newborn

Introduction: Persistent pulmonary hypertension of the newborn (PPHN) was first described by Gersony et al 1 of persistence of the fetal circulation in 1969. It is a clinical syndrome characterized by respiratory distress, hypoxemia, elevated pulmonary vascular resistance and a right to left shunting of venous blood across the foramen ovale and/or ductus arteriosus. The etiology of PPHN is not ...

Persistent Pulmonary Hypertension of the Newborn (pphn)

Persistent Pulmonary Hypertension in the Newborn

Persistent pulmonary hypertension of the newborn (PPHN) is characterized by elevated pulmonary vascular resistance resulting in right-to-left shunting of blood and hypoxemia. PPHN is often secondary to parenchymal lung disease (such as meconium aspiration syndrome, pneumonia or respiratory distress syndrome) or lung hypoplasia (with congenital diaphragmatic hernia or oligohydramnios) but can al...

Prevalence of Persistent Pulmonary Hypertension of the Newborn and Associated Factors in Term Neonates Born in Southeast of Iran, 2020

 Background and purpose: Infants with persistent pulmonary hypertension (PPHN) are readmitted to hospital three times more than other infants or die after discharge. The disease imposes a high cost on families and health systems. In this study, for the first time, the prevalence of PPHN and associated factors were investigated in mature neonates born in southeast of Iran. Materials and methods...

Diagnosis and management of persistent pulmonary hypertension of the newborn.

Persistent pulmonary hypertension of new born (PPHN) is associated with mortality and morbidity; it may be idiopathic or secondary to a number of conditions. The mainstay of diagnosis and to exclude structural abnormalities is echocardiography. Brain type natriuretic peptide (BNP) levels are elevated in PPHN, but are insufficiently sensitive to contribute to routine diagnosis. Management includ...